The Amino Acid Composition of Bence-Jones Protein.
نویسندگان
چکیده
منابع مشابه
The Amino Acid Sequence of a K Type Bence-Jones Protein
The amino acid sequence of the human K Bence-Jones protein Ag containing 214 residues has been determined by a combination of four procedures: sequence analysis of the tryptic and of the chymotryptic peptides of the carboxymethylated protein described earlier and partial sequence analysis of the tryptic peptides of the aminoethylated protein and of the peptic peptides of the oxidized protein de...
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Bence Jones protein injected into rabbits was excreted rapidly into the urine. The excreted protein retained the physicochemical and immunochemical properties of the injected Bence Jones protein. In spite of the rapid excretion, a significant portion of the injected Bence Jones protein was found to be metabolized. After reinjection of radioactive Bence Jones protein into the donor patient, only...
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The complete amino acid sequence of an amyloidogenic Bence Jones protein (NIG-84) from an individual with myeloma-associated systemic amyloidosis has been determined. The protein, with a blocked N-terminus, represents a complete light chain consisting of 217 residues and it has a structural feature characteristic of the V lambda II subgroup. In addition to a two-residue insertion at positions 2...
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Plasma cell disorders are important in the differential diagnosis of acute kidney injury and of renal impairment with proteinuria. One or more of several mechanisms can be involved, such as cast nephropathy, deposition of monoclonal immunoglobulins, formation of amyloid fibrils, hypercalcaemia, hyperuricaemia and a variety of tubular syndromes. Various tests, such as serum electrophoresis and i...
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The complete amino acid sequence and the location of the disulfide bridges of the human X Bence-Jones protein Sh containing 213 residues have been determined by a combination of three procedures: sequence analysis of the tryptic peptides of the aminoethylated protein and of the chymotryptic peptides of the carboxymethylated protein described earlier and partial sequence analysis of the peptic p...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1952
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.06-1232